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Pre-term birth - many of risk factors are associated with low vitamin D

Women are nine times more likely to give birth early if they have a multiple pregnancy (twins, triplets)[7]
An interval of less than 6 months between pregnancies [7]
[7] Mayo Clinic. Premature birth. Available at: http://www.mayoclinic.org/diseases-conditions/premature-birth/basics/risk-factors/con-20020050 (2014, accessed 9 December 2014).

Vitamin D Receptor is a major factor in preterm births - see following

Preterm birth problems if poor Vitamin D Receptor

Risk
increase
Health Problem
34Preterm birth seems too large
3.3 Pre-term birth


http://www.statisticbrain.com/premature-birth-statistics/
2<6 weeks 80 % survive, but
Develop a severe disability (cerebral palsy) 22 %
Develop a moderate disability (special needs) 24 %
Develop a mild disability (low IQ, vision) 34 %

http://www.marchofdimes.org/research/vitamin-d-to-combat-preterm-birth.aspx
2X more preterm birth if black skin

Prevention of Preterm Birth recent increase in preterm birth rate

Image


Healthy pregnancies need lots of vitamin D in VitaminDWiki has the following summary
Most were taking 2,000 to 7,000 IU daily for >50% of pregnancy
   Click on hyperlinks for details

Problem
Vit. D
Reduces
Evidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial

Pre-term birth - many of risk factors are associated with low vitamin D        
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